Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
piuC iron transport protein	M1V	-	-	Acinetobacter baumannii	cefiderocol	Reslit	Candidate
piuC siderophore utilization	R201H	-	-	Pseudomonas aeruginosa, Acinetobacter spp.	cefiderocol	Reslit	Candidate
piuC PiuC iron-dependent oxygenase (a TonB-dependent transporter)	S116F	-	entailing a switch from an amino acid with polar uncharged side chain (serine) to one with a hydrophobic side chain (phenylalanine), which could be involved in the binding of the siderophore	Pseudomonas aeruginosa	cefiderocol	Reslit	Candidate
piuD	G354V	-	TonB-dependent siderophore receptor PiuD	Pseudomonas aeruginosa	cefiderocol	Reference Gene Catalog	Established
piuD	Q604*	-	TonB-dependent siderophore receptor PiuD	Pseudomonas aeruginosa	cefiderocol	Reference Gene Catalog	Established
pks8 polyketide synthase	L169V	-	-	Mycobacterium tuberculosis	bedaquiline	Reslit	Candidate
plcC phospholipase C	Q462R	-	unknown	Mycobacterium tuberculosis	capreomycin	Reslit	Candidate
pldA phospholipase	T200T	-	outer membrane disorganization	Acinetobacter baumannii	colistin	Reslit	Candidate
plsX phosphate acyl-ACP acyltransferase	H57Y	-	-	Streptococcus pneumoniae	trimethoprim	Reslit	Candidate
pmpM efflux pump regulator	-	G4A	-	Pseudomonas aeruginosa	fluoroquinolones	Reslit	Candidate