Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
pmrB two-component regulatory system histidine kinase | A252G | - | - | Klebsiella pneumoniae | colistin | Reslit | Candidate |
pmrB two-component system histidine kinase | A256G | - | deleterious | Klebsiella pneumoniae | colistin | Reslit | Candidate |
pmrB two-component system sensor kinase | A262P | - | constitutive activation | Acinetobacter baumannii | colistin | Reslit | Candidate |
pmrB two-component system | A330P | - | disruption of the two-component regulatory system | Pseudomonas aeruginosa | colistin | Reslit | Candidate |
pmrB two-component system response regulator | A360V | - | - | Escherichia coli | colistin | Reslit | Candidate |
| A412V | - | - | Acinetobacter baumannii | colistin | Reslit | Candidate | |
pmrB histidine kinase of the pmrCAB two-component system | A444V | - | destabilizing | Acinetobacter baumannii | colistin | Reslit | Candidate |
pmrB sensor kinase | A54V | - | gain-of-function, two-component system sensor histidine kinase PmrB | Pseudomonas aeruginosa | colistin | Reference Gene CatalogReslit | Confirmed |
pmrB sensor kinase | A95T | - | gain-of-function | Pseudomonas aeruginosa | colistin | Reslit | Candidate |
| ALNQLV129del | - | two-component system sensor histidine kinase PmrB | Klebsiella pneumoniae | colistin | Reference Gene Catalog | Established |
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