Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
pmrB histidine kinase | C340F | - | mutant PmrB leads to cross-resistance to aminoglycosides and colistin | Pseudomonas aeruginosa | polymyxin b | Reslit | Candidate |
pmrB two-component system sensor kinase | C395A | - | - | - | polymyxins | Reslit | Candidate |
| C84R | - | two-component system sensor histidine kinase PmrB | Escherichia coli | colistin | Reference Gene Catalog | Established | |
pmrB two-component system histidine kinase | C84Y | - | two-component system sensor histidine kinase PmrB | E. coli, Escherichia coli | colistin | Reference Gene CatalogReslit | Confirmed |
pmrB two-component system response regulator | D133G | - | - | Acinetobacter baumannii | polymyxins | Reslit | Candidate |
pmrB two-component system histidine kinase | D149Y | - | - | E. coli | colistin | Reslit | Candidate |
pmrB two-component system sensor kinase | D150H | - | - | - | colistin | Reslit | Candidate |
pmrB two-component regulatory system histidine kinase | D150V | - | - | Klebsiella pneumoniae | colistin | Reslit | Candidate |
pmrB Two-component system sensor kinase | D150Y | - | - | Klebsiella pneumoniae | polymyxins | Reslit | Candidate |
pmrB sensor kinase of two-component system | D21A | - | - | Klebsiella pneumoniae | colistin | Reslit | Candidate |
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