Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| D250Y | - | two-component system sensor histidine kinase PmrB | Salmonella enterica | colistin | Reference Gene Catalog | Established | |
pmrB transmembrane protein | D283G | - | - | Escherichia coli | colistin | Reslit | Supported |
pmrB two-component system sensor kinase | D313N | - | two-component system sensor histidine kinase PmrB | Klebsiella pneumoniae, Acinetobacter baumannii | colistinpolymyxins | Reference Gene CatalogReslit | Confirmed |
pmrB sensor histidine kinase of the PmrAB two-component system | D315N | - | - | Escherichia coli | colistin | Reslit | Candidate |
| D47del | - | two-component system sensor histidine kinase PmrB | Pseudomonas aeruginosa | colistin | Reference Gene Catalog | Established | |
pmrB sensor kinase of two-component system, PmrAB | D47G | - | confers resistance to colistin | Pseudomonas aeruginosa | colistin | Reslit | Candidate |
pmrB two-component sensor kinase | D47N | mutations in pmrB contribute to colistin resistance | Pseudomonas aeruginosa | colistin | Reslit | Candidate | |
pmrB histidine kinase | E121A | - | Target modification, two-component system sensor histidine kinase PmrB | Salmonella enterica | polymyxin bcolistin | Reference Gene CatalogResFinder DatabaseReslit | Confirmed |
pmrB two-component system histidine kinase | E121K | - | two-component system sensor histidine kinase PmrB | Escherichia coli | colistin | Reference Gene CatalogReslit | Confirmed |
| E121Q | - | two-component system sensor histidine kinase PmrB | Escherichia coli | colistin | Reference Gene Catalog | Established |
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