Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrB two-component system sensor kinase	T232I	-	two-component system sensor histidine kinase PmrB	Acinetobacter baumannii	polymyxin bcolistin	Reference Gene CatalogReslit	Confirmed
pmrB histidine kinase	T235I	-	associated with stable resistance, two-component system sensor histidine kinase PmrB	Acinetobacter baumannii	polymyxin bcolistin	Reference Gene CatalogReslit	Confirmed
pmrB transmembrane protein	T235N	-	-	Escherichia coli, Acinetobacter baumannii	colistin	Reslit	Candidate
pmrB regulatory protein	T240M	-	-	-	colistin	Reslit	Candidate
pmrB two-component system response regulator	T246A	-	enhanced ATP binding affinity and protein stability	Klebsiella pneumoniae	colistinpolymyxin bpolymyxins	Reslit	Supported
pmrB sensor kinase	T253M	-	gain-of-function, two-component system sensor histidine kinase PmrB	Pseudomonas aeruginosa	colistin	Reference Gene CatalogReslit	Confirmed
pmrB two-component system histidine kinase	T269P	-	-	Acinetobacter baumannii	colistin	Reslit	Candidate
pmrB two-component system histidine kinase	T296S	-	altered	Klebsiella aerogenes	colistin	Reslit	Candidate
pmrB	T343A	-	two-component system sensor histidine kinase PmrB	Pseudomonas aeruginosa	colistin	Reference Gene Catalog	Established
pmrB two-component sensor kinase	T4A	-	activating mutation	Pseudomonas aeruginosa	colistin	Reslit	Candidate