Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
pncA pyrazinamidase | D8L | - | disrupts catalytic activity | Mycobacterium tuberculosis, Mycobacterium bovis | pyrazinamide | Reslit | Candidate |
pncA pyrazinamidase | D8N | single resistance variant | Mycobacterium tuberculosis | pyrazinamidepza | Card DatabaseReslit | Confirmed | |
| D8V | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| D8Y | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| E107* | - | nonsense mutation | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| E111* | - | nonsense mutation | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
pncA pyrazinamidase | E112K | - | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Candidate |
pncA pyrazinamidase | E127* | - | nonsense mutation | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
| E127D | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| E144* | - | nonsense mutation | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established |
Page 969 of 1344 (13,437 results)