Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
pncA pyrazinamidase | N137S | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Candidate | |
pncA pyrazinamidase | N149fs | - | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Candidate |
| N149I | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| N149Y | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
pncA Pyrazinamidase | N36S | - | - | Mycobacterium tuberculosis | pza | Reslit | Candidate |
pncA pyrazinamidase | N76H | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Supported | |
| P115A | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| P115R | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
pncA pyrazinamidase | P46Q | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Candidate | |
pncA Pyrazinamidase | P54L | loss of PZAse activity, single resistance variant | Mycobacterium tuberculosis | pzapyrazinamide | Card DatabaseReslit | Confirmed |
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