Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
pncA pyrazinamidase | P62T | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
pncA pyrazinamidase | P69L | single resistance variant | Mycobacterium tuberculosis | pyrazinamidepza | Card DatabaseReslit | Confirmed | |
pncA pyruvate carboxylase | P69Q | - | single resistance variant | Mycobacterium bovis, Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
| P69R | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
pncA pyrazinamidase (PZase) | P69T | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Candidate | |
| P70A | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| P70S | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| P77S | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| Q10* | - | nonsense mutation | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| Q10E | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established |
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