Topoisomerase sequences of coagulase-negative staphylococcal isolates resistant to ciprofloxacin or trovafloxacin.

PMID: 103902141999

Key Findings

Mutation in gyrA codon 84 associated with ciprofloxacin resistance.

0gene entries

12mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S84L	-	-	Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus simulans	Ciprofloxacin	Reslit	-
grlA	S80L	TCT->CTT	-	Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus simulans	Ciprofloxacin	Reslit	-
grlA	S84L	TCT->CTT	-	Staphylococcus epidermidis, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus simulans	Ciprofloxacin	Reslit	-