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Contribution of topoisomerase IV and DNA gyrase mutations in Streptococcus pneumoniae to resistance to novel fluoroquinolones.

PMID: 104289261999

0gene entries

7mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parC	D83Y	-	-	Streptococcus pneumoniae	Ciprofloxacin\|Levofloxacin\|Sparfloxacin\|Trovafloxacin	Reslit	-
gyrA	S114G	-	-	Streptococcus pneumoniae	Ciprofloxacin\|Levofloxacin	Reslit	-
parE	I493L	-	-	Streptococcus pneumoniae	Ciprofloxacin\|Levofloxacin\|Sparfloxacin\|Trovafloxacin	Reslit	-
parE	D435N	-	-	Streptococcus pneumoniae	Ciprofloxacin\|Levofloxacin\|Sparfloxacin\|Trovafloxacin	Reslit	-
parC	N91D	-	-	Streptococcus pneumoniae	Ciprofloxacin\|Levofloxacin	Reslit	-
parC	S79Y	-	-	Streptococcus pneumoniae	Ciprofloxacin\|Levofloxacin\|Sparfloxacin\|Trovafloxacin	Reslit	-
parE	I460V	-	-	Streptococcus pneumoniae	Ciprofloxacin\|Levofloxacin\|Sparfloxacin\|Trovafloxacin	Reslit	-