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Cloning and nucleotide sequence of the DNA gyrase (gyrA) gene from Mycoplasma hominis and characterization of quinolone-resistant mutants selected in vitro with trovafloxacin.

PMID: 109918512000

0gene entries

8mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	A189E	-	-	Mycoplasma hominis	Ciprofloxacin\|Ofloxacin\|Sparfloxacin\|Trovafloxacin	Reslit	-
parC	E95Q	-	-	-	Ciprofloxacin\|Ofloxacin\|Sparfloxacin\|Trovafloxacin	Reslit	-
gyrA	S153L	-	-	Mycoplasma hominis	Ciprofloxacin\|Ofloxacin\|Sparfloxacin\|Trovafloxacin	Reslit	-
parE	E466K	-	-	Mycoplasma hominis	Ciprofloxacin\|Ofloxacin\|Sparfloxacin\|Trovafloxacin	Reslit	-
parC	S91I	-	-	-	Ciprofloxacin\|Ofloxacin\|Sparfloxacin\|Trovafloxacin	Reslit	-
parC	S92P	-	-	-	Ciprofloxacin\|Ofloxacin\|Sparfloxacin\|Trovafloxacin	Reslit	-
gyrA	E157K	-	-	Mycoplasma hominis	Ciprofloxacin\|Ofloxacin\|Sparfloxacin\|Trovafloxacin	Reslit	-
parE	L446F	-	-	Mycoplasma hominis	Ofloxacin\|Pefloxacin	Reslit	-