Enhanced expression of the multidrug efflux pumps AcrAB and AcrEF associated with insertion element transposition in Escherichia coli mutants Selected with a fluoroquinolone.
PMID: 113028122001
Key Findings
The study identifies the enhanced expression of multidrug efflux pumps AcrAB and AcrEF in Escherichia coli mutants selected with a fluoroquinolone, associated with insertion element transposition. The mutations in acrR and acrS lead to increased resistance to various antibiotics.
2gene entries
0mutation entries
AMR Genes
| Gene Name | Alleles | Encodes | Confers Resistance To | Organisms | Database | Validation Status |
|---|---|---|---|---|---|---|
| acrab | 1 | multidrug efflux pump | fluoroquinolones |
| Reslit | - |
| acref | 1 | multidrug efflux pump | fluoroquinolonestetracyclinechloramphenicolampicillincefuroximetrimethoprimerythromycinclarithromycinazithromycin+3 more |
| Reslit | - |