All detectable high-molecular-mass penicillin-binding proteins are modified in a high-level beta-lactam-resistant clinical isolate of Streptococcus mitis.

PMID: 114082262001

Key Findings

The resistant strain 127R shows an I-to-T change at position 358 in the PB domain.

0gene entries

4mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp1a	I358T	-	-	Streptococcus mitis	Beta-lactam	Reslit	-
pbp2x	T338P	-	-	Streptococcus mitis	Beta-lactam	Reslit	-
pbp2b	T446A	-	-	Streptococcus mitis	Beta-lactam	Reslit	-
pbp2b	A619G	-	-	Streptococcus mitis	Beta-lactam	Reslit	-