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Key Findings
Mutations in rpoB confer rifampin resistance
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| H481N | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RifampinRIFAMPIN | ReslitReference Gene Catalog | - | |
| D471Y | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RIFAMPIN | Reference Gene Catalog | - | |
| A477D | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RIFAMPIN | Reference Gene Catalog | - | |
| S464P | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RIFAMPIN | Reference Gene Catalog | - | |
| Q468L | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RIFAMPIN | Reference Gene Catalog | - | |
| D471E | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RIFAMPIN | Reference Gene Catalog | - | |
| N474L | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RIFAMPIN | Reference Gene Catalog | - | |
| H481Y | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RIFAMPIN | Reference Gene Catalog | - | |
| S486L | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RIFAMPIN | Reference Gene Catalog | - | |
| Q468R | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RIFAMPIN | Reference Gene Catalog | - | |
| D471G | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RIFAMPIN | Reference Gene Catalog | - | |
| I527F | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RIFAMPIN | Reference Gene Catalog | - | |
| A477V | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | BETA-LACTAM/RIFAMPIN | Reference Gene Catalog | - | |
| R484H | - | DNA-directed RNA polymerase subunit beta RpoB | Staphylococcus aureus | RIFAMPIN | Reference Gene Catalog | - |
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