Epidemiology of nalidixic acid resistance and TEM-1- and TEM-52-mediated ampicillin resistance of Shigella sonnei isolates obtained in Korea between 1980 and 2000.

PMID: 146384722003Korea

Key Findings

The study identified TEM-1 and TEM-52 beta-lactamases as mediators of ampicillin resistance in Shigella sonnei isolates, and a single point mutation in gyrA (Ser83→Leu) as the mechanism of nalidixic acid resistance.

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2gene entries

1mutation entry

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaTEM	2	beta-lactamase	Ampicillin	Shigella sonnei	Reslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S83L	-	-	Shigella sonnei	Nalidixic acid	Reslit	-

Browse Papers

Epidemiology of nalidixic acid resistance and TEM-1- and TEM-52-mediated ampicillin resistance of Shigella sonnei isolates obtained in Korea between 1980 and 2000.

AMR Genes

AMR Mutations