Macrolide- and telithromycin-resistant Streptococcus pyogenes, Belgium, 1999-2003.

PMID: 159632922005Europe|Belgium

Key Findings

The study identifies erm(B) and mef(A) as the primary mechanisms of macrolide resistance in Streptococcus pyogenes, with a specific H118R mutation in erm(B) linked to telithromycin resistance.

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2gene entries

1mutation entry

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
erm(B)	1	erythromycin ribosome methylase	ErythromycinClindamycinAzithromycin	Streptococcus pyogenes	Reslit	-
mef(A)	1	efflux pump	ErythromycinAzithromycin	Streptococcus pyogenes	Reslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
erm(B)	H118R	-	-	Streptococcus pyogenes	Telithromycin	Reslit	-

Browse Papers

Macrolide- and telithromycin-resistant Streptococcus pyogenes, Belgium, 1999-2003.

AMR Genes

AMR Mutations