Correlation of penicillin Binding Protein 2a Detection with Oxacillin Resistance in Staphylococcus aureus and discovery of a novel penicillin Binding Protein 2a mutation.

PMID: 161451042005

Key Findings

The study correlated PBP2a detection with oxacillin resistance in Staphylococcus aureus and discovered a novel PBP2a mutation (M483I) in an oxacillin-susceptible isolate, highlighting the complexity of resistance mechanisms.

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2gene entries

1mutation entry

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
mecA	1	penicillin binding protein 2a	OxacillinMETHICILLIN	Staphylococcus aureus	Reference Gene CatalogReslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
mecA	M483I	-	may be associated with a change in the function of PBP2a resulting in oxacillin susceptibility	Staphylococcus aureus	Oxacillin	Reslit	-

Browse Papers

Correlation of penicillin Binding Protein 2a Detection with Oxacillin Resistance in Staphylococcus aureus and discovery of a novel penicillin Binding Protein 2a mutation.

AMR Genes

AMR Mutations