Efficacy and potential for resistance selection of antipseudomonal treatments in a mouse model of lung infection by hypermutable Pseudomonas aeruginosa.

PMID: 164952602006

Key Findings

GyrA Thr-83-Ile mutation was observed in in vitro and in vivo ciprofloxacin-resistant mutants.

0gene entries

3mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	-	G248A	-	-	Ciprofloxacin	Reslit	-
gyrB	-	T1398C	-	Pseudomonas aeruginosa	Ciprofloxacin	Reslit	-