Pharmacokinetic/pharmacodynamic analysis of the influence of inoculum size on the selection of resistance in Escherichia coli by a quinolone in a mouse thigh bacterial infection model.

PMID: 194874392009

Key Findings

The gyrA gene was studied for mutations that confer resistance to quinolones.

0gene entries

1mutation entry

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S83L	GCT->TTT	-	Escherichia coli	Fluoroquinolones	Reslit	-