Browse Papers

Explore scientific publications on antimicrobial resistance

Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production

PMID: 208557242010

Key Findings

Mutation in lpxD leads to complete loss of LPS production and colistin resistance.

0gene entries

14mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
lpxD	317fs	-	complete loss of LPS production	Acinetobacter baumannii	Colistin	Reslit	-
lpxC	P30L	-	UDP-3-O-acyl-N-acetylglucosamine deacetylase LpxC, single resistance variant	Acinetobacter baumannii	ColistinCOLISTIN	ReslitReference Gene CatalogCard Database	-
lpxC	45fs	-	-	Acinetobacter baumannii	Colistin	Reslit	-
lpxC	285fs	-	-	Acinetobacter baumannii	Colistin	Reslit	-
lpxA	G68D	-	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase LpxA, single resistance variant	Acinetobacter baumannii	COLISTIN	Reference Gene CatalogCard Database	-
lpxA	D233Ter	-	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase LpxA	Acinetobacter baumannii	COLISTIN	Reference Gene Catalog	-
lpxA	H159D	-	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase LpxA, single resistance variant	Acinetobacter baumannii	COLISTIN	Reference Gene CatalogCard Database	-
lpxA	Q72K	-	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase LpxA, single resistance variant	Acinetobacter baumannii	COLISTIN	Reference Gene CatalogCard Database	-
lpxD	K137fs	-	frameshift mutation	Acinetobacter baumannii	-	Card Database	-