In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient.

PMID: 209213062010

Key Findings

missense mutation in adeR leads to overexpression of adeB

6gene entries

2mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaOXA	2	oxacillinase	ImipenemMeropenemIMIPENEMMEROPENEMCARBAPENEM	Acinetobacter baumannii Escherichia coli	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	-

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
adeR	D20N	-	overexpression of adeB, efflux system response regulator transcription factor AdeR	Acinetobacter baumannii	TigecyclineEFFLUX	ReslitReference Gene Catalog	-