Characterisation of the genes encoding resistance to metronidazole (rdxA and frxA) and clarithromycin (the 23S-rRNA genes) in South African isolates of Helicobacter pylori.

PMID: 218015042011

Key Findings

Helicobacter pylori frxA mutation conferring resistance to metronidazole; CARD accession: CARD:3007059

1gene entry

2mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
rdxA	1	oxygen-insensitive NADPH nitroreductase	Metronidazole	Helicobacter pylori	Reslit	-

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
fxra	L39Ter	-	nonsense mutation	Helicobacter pylori	Metronidazole	Card Database	-
fxra	E199Ter	-	nonsense mutation	Helicobacter pylori	Metronidazole	Card Database	-