First description of the qnrS-like (qnrS5) gene and analysis of quinolone resistance-determining regions in motile Aeromonas spp. from diseased fish and water.

PMID: 220243392012South Korea

Key Findings

The study identified a novel qnrS-like gene, qnrS5, which confers resistance to nalidixic acid and ciprofloxacin in Aeromonas spp. Additionally, chromosomal mutations in gyrase and topoisomerase IV genes were found to contribute to quinolone resistance.

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10gene entries

3mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
qnrS	5	quinolone resistance protein	CiprofloxacinQUINOLONECIPROFLOXACIN	Aeromonas spp. Aeromonas sobria Aeromonas hydrophila	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S83I	-	-	Aeromonas spp.	Nalidixic acid\|Ciprofloxacin	Reslit	-
parC	S92I	-	-	-	Nalidixic acid\|Ciprofloxacin	Reslit	-

Browse Papers

First description of the qnrS-like (qnrS5) gene and analysis of quinolone resistance-determining regions in motile Aeromonas spp. from diseased fish and water.

AMR Genes

AMR Mutations