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Explore scientific publications on antimicrobial resistance

Characterizations of clinical isolates of clostridium difficile by toxin genotypes and by susceptibility to 12 antimicrobial agents, including fidaxomicin (OPT-80) and rifaximin: a multicenter study in Taiwan.

PMID: 225082992012

0gene entries

22mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrB	S416A	-	-	-	Moxifloxacin	Reslit	-
gyrB	E466K	-	single resistance variant	Clostridium ljungdahlii	MoxifloxacinFluoroquinolones	ReslitCard Database	-
gyrA	T82I	-	-	Clostridium difficile	Moxifloxacin\|Ciprofloxacin\|Levofloxacin	Reslit	-
gyrA	D71V	-	DNA gyrase subunit A GyrA	Clostridioides difficile	QUINOLONE	Reference Gene Catalog	-
gyrA	D81N	-	DNA gyrase subunit A GyrA, single resistance variant	Clostridioides difficile	QUINOLONEFluoroquinolones	Reference Gene CatalogCard Database	-
gyrA	D71G	-	DNA gyrase subunit A GyrA, single resistance variant	Clostridioides difficile	QUINOLONEFluoroquinolones	Reference Gene CatalogCard Database	-
gyrA	T82A	-	DNA gyrase subunit A GyrA, single resistance variant	Clostridioides difficile	QUINOLONEFluoroquinolones	Reference Gene CatalogCard Database	-
gyrB	R377G	-	DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB, single resistance variant	Clostridioides difficile, Clostridium ljungdahlii	QUINOLONEFluoroquinolones	Reference Gene CatalogCard Database	-
gyrA	D103N	-	single resistance variant	Clostridioides difficile	Fluoroquinolones	Card Database	-
gyrB	V423F	-	single resistance variant	Clostridium ljungdahlii	Fluoroquinolones	Card Database	-
gyrA	R90K	-	single resistance variant	Clostridioides difficile	Fluoroquinolones	Card Database	-
gyrB	R389P	-	single resistance variant	Clostridium ljungdahlii	Fluoroquinolones	Card Database	-
gyrB	D409N	-	single resistance variant	Clostridium ljungdahlii	Fluoroquinolones	Card Database	-
gyrB	D465Y	-	single resistance variant	Clostridium ljungdahlii	Fluoroquinolones	Card Database	-
gyrA	Q123K	-	single resistance variant	Clostridioides difficile	Fluoroquinolones	Card Database	-
gyrB	E399K	-	single resistance variant	Clostridium ljungdahlii	Fluoroquinolones	Card Database	-
gyrB	R457T	-	single resistance variant	Clostridium ljungdahlii	Fluoroquinolones	Card Database	-