Impact of amino acid substitutions in B subunit of DNA gyrase in Mycobacterium leprae on fluoroquinolone resistance.

PMID: 230718502012

Key Findings

Mycobacterium leprae gyrB conferring resistance to fluoroquinolones; CARD accession: CARD:3003304

0gene entries

4mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrB	D464N	GAT->AAT	single resistance variant	Mycobacterium leprae	FluoroquinolonesOfloxacin\|Moxifloxacin\|Sitafloxacin\|Ciprofloxacin\|Levofloxacin	Card DatabaseReslit	-
gyrB	N502D	-	single resistance variant	Mycobacterium leprae	Fluoroquinolones	Card Database	-
gyrB	E504V	-	single resistance variant	Mycobacterium leprae	Fluoroquinolones	Card Database	-