Prevalence of Fosfomycin Resistance and Mutations in murA, glpT, and uhpT in Methicillin-Resistant Staphylococcus aureus Strains Isolated from Blood and Cerebrospinal Fluid Samples.

PMID: 267931792015

Key Findings

Staphylococcus aureus UhpT with mutation conferring resistance to fosfomycin; CARD accession: CARD:3003902

0gene entries

30mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
uhpT	W228Ter	-	nonsense mutation	Staphylococcus aureus	Fosfomycin	Card Database	-
uhpT	T1273C	-	-	Staphylococcus aureus	Fosfomycin	Reslit	-
uhpT	G335A	-	-	Staphylococcus aureus	Fosfomycin	Reslit	-
uhpT	Y314Ter	-	nonsense mutation	Staphylococcus aureus	Fosfomycin	Card Database	-
glpT	W137R	-	single resistance variant	Staphylococcus aureus	Fosfomycin	ReslitCard Database	-
uhpT	G683A	-	-	Staphylococcus aureus	Fosfomycin	Reslit	-
uhpT	C942A	-	-	Staphylococcus aureus	Fosfomycin	Reslit	-
uhpT	G1073T	-	-	Staphylococcus aureus	Fosfomycin	Reslit	-
glpT	A100V	-	glycerol-3-phosphate transporter GlpT, single resistance variant	Staphylococcus aureus	FOSFOMYCINFosfomycin	Reference Gene CatalogCard Database	-
glpT	W355Ter	-	glycerol-3-phosphate transporter GlpT, nonsense mutation	Staphylococcus aureus	FOSFOMYCINFosfomycin	Reference Gene CatalogCard Database	-
murA	L42Ter	-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA, nonsense mutation	Staphylococcus aureus	FOSFOMYCINFosfomycin	Reference Gene CatalogCard Database	-
glpT	F3I	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
glpT	V213I	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
glpT	L27F	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
glpT	G352D	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
murA	Q362R	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
murA	V65L	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
murA	G257D	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
murA	E291D	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
murA	D278E	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
murA	T396N	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
uhpT	G358V	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
uhpT	G112E	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
uhpT	W425R	-	single resistance variant	Staphylococcus aureus	Fosfomycin	Card Database	-
murA	-	T125A	-	Staphylococcus aureus	Fosfomycin	Reslit	-
glpT	-	T409C	-	Staphylococcus aureus	Fosfomycin	Reslit	-

Browse Papers

Prevalence of Fosfomycin Resistance and Mutations in murA, glpT, and uhpT in Methicillin-Resistant Staphylococcus aureus Strains Isolated from Blood and Cerebrospinal Fluid Samples.

AMR Mutations