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Explore scientific publications on antimicrobial resistance

Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness.

PMID: 281456842017

Key Findings

Mutations in penA gene lead to resistance to cephalosporins.

0gene entries

5mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
penA	A501S	-	-	Neisseria gonorrhoeae	Cefixime\|Ceftriaxone	Reslit	-
penA	A501R	-	-	Neisseria gonorrhoeae	Cefixime\|Ceftriaxone	Reslit	-
penA	A501P	-	-	Neisseria gonorrhoeae	Cefixime\|Ceftriaxone	Reslit	-
penA	A501T	-	-	Neisseria gonorrhoeae	Cefixime\|Ceftriaxone	Reslit	-
penA	A501V	-	-	Neisseria gonorrhoeae	Cefixime\|Ceftriaxone	Reslit	-