Molecular Epidemiology and Colistin Resistant Mechanism of mcr-Positive and mcr-Negative Clinical Isolated Escherichia coli.

PMID: 292500392017China

Key Findings

The study identifies mcr-1 as a key gene for colistin resistance in E. coli, and reports mutations in pmrB and phoQ as additional mechanisms in mcr-negative isolates.

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1gene entry

8mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
mcr-1	1	Phosphoethanolamine transferase	Colistin	Escherichia coli	Reslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrB	E123D	-	-	Escherichia coli	Colistin	Reslit	-
phoQ	N346K	-	-	-	Colistin	Reslit	-
pmrB	Y315F	-	-	Escherichia coli	Colistin	Reslit	-

Browse Papers

Molecular Epidemiology and Colistin Resistant Mechanism of mcr-Positive and mcr-Negative Clinical Isolated Escherichia coli.

AMR Genes

AMR Mutations