Cl415, a carbapenem-resistant Acinetobacter baumannii isolate containing four AbaR4 and a new variant of AbGRI2, represents a novel global clone 2 strain.

PMID: 347415942022Lebanon

Key Findings

The study identifies the presence of four copies of the oxa23 carbapenem resistance gene, blaTEM, and aphA1 in the carbapenem-resistant Acinetobacter baumannii isolate Cl415. Additionally, mutations in the gyrA and parC genes were found to contribute to fluoroquinolone resistance.

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1gene entry

2mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
aphA1	1	aminoglycoside phosphotransferase	Aminoglycoside	Acinetobacter baumannii	Reslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parC	S84L	-	-	Acinetobacter baumannii	Fluoroquinolones	Reslit	-
gyrA	S81L	-	-	Acinetobacter baumannii	Fluoroquinolones	Reslit	-

Browse Papers

Cl415, a carbapenem-resistant Acinetobacter baumannii isolate containing four AbaR4 and a new variant of AbGRI2, represents a novel global clone 2 strain.

AMR Genes

AMR Mutations