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Nucleotide substitutions in the mexR, nalC and nalD regulator genes of the MexAB-OprM efflux pump are maintained in Pseudomonas aeruginosa genetic lineages.

PMID: 355368362022

0gene entries

12mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
nalC	E153Q	-	-	Pseudomonas aeruginosa	Multiple antibiotics	Reslit	-
nalD	A46T	-	-	Pseudomonas aeruginosa	Multiple antibiotics	Reslit	-
nalC	G71E	-	-	Pseudomonas aeruginosa	Multiple antibioticsCarbapenem\|Cephalosporin\|Fluoroquinolones	Reslit	-
nalD	D180D	-	-	Pseudomonas aeruginosa	Carbapenem\|Cephalosporin\|Fluoroquinolones	Reslit	-
mexR	V126E	-	-	Pseudomonas aeruginosa	Carbapenem\|Cephalosporin\|FluoroquinolonesMultiple antibiotics	Reslit	-
nalC	A123A	-	-	Pseudomonas aeruginosa	Multiple antibiotics	Reslit	-
nalD	C92C	-	-	Pseudomonas aeruginosa	Carbapenem\|Cephalosporin\|Fluoroquinolones	Reslit	-
nalC	S209R	-	-	Pseudomonas aeruginosa	Carbapenem\|Cephalosporin\|Fluoroquinolones	Reslit	-
nalD	I111I	-	-	Pseudomonas aeruginosa	Carbapenem\|Cephalosporin\|Fluoroquinolones	Reslit	-
nalC	-	C360G	-	Pseudomonas aeruginosa	Multiple antibiotics	Reslit	-