Immunosuppression broadens evolutionary pathways to drug resistance and treatment failure during Acinetobacter baumannii pneumonia in mice.

PMID: 356187742022

Key Findings

The gyrA (A117E) mutation contributes to increased ciprofloxacin resistance.

0gene entries

3mutation entries

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	A117E	-	-	Acinetobacter baumannii	Ciprofloxacin	Reslit	-
gyrB	Q447H	-	-	Acinetobacter baumannii	Ciprofloxacin	Reslit	-
lpxD	E117K	-	-	Acinetobacter baumannii	Ciprofloxacin	Reslit	-