Comparative genomic analysis of Flavobacterium species causing columnaris disease of freshwater fish in Thailand: insights into virulence and resistance mechanisms.

PMID: 403899232025Thailand

Key Findings

The study identified a tetracycline resistance gene (tetA_2) in a F. covae isolate and mutations in the quinolone resistance-determining regions of gyrA associated with decreased susceptibility to quinolones and fluoroquinolones in Flavobacterium species causing columnaris disease in Thailand.

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1gene entry

36mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
tetA	1	tetracycline resistance protein	Tetracycline	Flavobacterium covae	Reslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S83F	-	-	Flavobacterium covae, Flavobacterium davisii, Flavobacterium oreochromis	Oxolinic acid\|EnrofloxacinFluoroquinolones\|Quinolone	Reslit	-
gyrA	S83A	-	-	Flavobacterium covae, Flavobacterium davisii, Flavobacterium oreochromis	Oxolinic acid\|EnrofloxacinFluoroquinolones\|Quinolone	Reslit	-
gyrA	S83V	-	-

Browse Papers

Comparative genomic analysis of Flavobacterium species causing columnaris disease of freshwater fish in Thailand: insights into virulence and resistance mechanisms.

AMR Genes

AMR Mutations