Resistance Mechanisms of Fluoroquinolone in Escherichia coli Isolated from Taihe Black-Boned Silky Fowl Exhibiting Abnormally Slow Fluoroquinolone Metabolism in Jiangxi, China.

PMID: 410099332025Jiangxi, China

Key Findings

This study identified the qnrS1 gene and several mutations in the QRDRs of GyrA and ParC as key contributors to fluoroquinolone resistance in E. coli isolates from Taihe Black-Boned Silky Fowl farms. Notably, the GyrA-S83Q mutation was reported as novel.

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1gene entry

4mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
qnrS	1	plasmid-mediated quinolone resistance	MoxifloxacinCiprofloxacinNorfloxacinLevofloxacin	Escherichia coli	Reslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	S83L	-	-	Escherichia coli	Flumequine\|Moxifloxacin\|Enrofloxacin\|Ciprofloxacin\|Norfloxacin\|Levofloxacin	Reslit	-
gyrA	D87N	-	-	Escherichia coli	Flumequine\|Moxifloxacin\|Enrofloxacin\|Ciprofloxacin\|Norfloxacin\|Levofloxacin	Reslit	-
gyrA	S83Q	-	-	Escherichia coli

Browse Papers

Resistance Mechanisms of Fluoroquinolone in Escherichia coli Isolated from Taihe Black-Boned Silky Fowl Exhibiting Abnormally Slow Fluoroquinolone Metabolism in Jiangxi, China.

AMR Genes

AMR Mutations