Killing two birds with one stone: emergence of colistin and cefiderocol resistance in a mucoid MDR Acinetobacter baumannii under colistin pressure.

PMID: 410985352025Europe

Key Findings

The study identifies OXA-23 as a carbapenemase in a multidrug-resistant Acinetobacter baumannii strain and reports mutations in pmrB and piuA that contribute to colistin and cefiderocol resistance, respectively.

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1gene entry

2mutation entries

AMR Genes

Gene Name	Alleles	Encodes	Confers Resistance To	Organisms	Database	Validation Status
blaOXA	1	beta-lactamase	Carbapenem	Acinetobacter baumannii	Reslit	-

AMR Mutations

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrB	A412V	-	-	Acinetobacter baumannii	Colistin	Reslit	-
piuA	D304G	A911G	-	-	Cefiderocol	Reslit	-

Browse Papers

Killing two birds with one stone: emergence of colistin and cefiderocol resistance in a mucoid MDR Acinetobacter baumannii under colistin pressure.

AMR Genes

AMR Mutations