Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
pncA pyrazinamidase | T142A | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
pncA pyrazinamidase | T142K | - | single resistance variant, multiple resistance variants | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
pncA pyrazinamidase | T142M | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed | |
pncA pyrazinamidase | T142P | - | loss of PZAse activity, single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
pncA pyrazinamidase | T142R | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
pncA pyrazinamidase/nicotinamidase | T153H | - | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Candidate |
pncA pyrazinamidase | T153I | - | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Candidate |
| T153N | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
pncA pyrazinamidase | T159A | - | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Candidate |
pncA pyrazinamidase | T160A | - | Mycobacterium tuberculosis | pyrazinamidepza | Reslit | Supported |
Page 1002 of 1344 (13,437 results)