Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| V9G | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| W119* | - | nonsense mutation | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| W119C | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
pncA Pyrazinamidase | W119G | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
pncA Pyrazinamidase | W119L | loss of PZAse activity, single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed | |
pncA Bacterial Fatty acid synthetase I | W119R | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
pncA pyrazinamidase | W12R | - | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Candidate |
pncA pyrazinamidase | W68* | - | nonsense mutation | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
pncA pyrazinamidase | W68C | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed | |
pncA pyrazinamidase | W68G | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
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