Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
pncA pyrazinamidase | Y34D | loss of PZAse activity, loss of activity, single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed | |
| Y34S | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| Y41* | - | nonsense mutation | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| Y41H | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| Y64* | - | nonsense mutation | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
pncA pyrazinamidase | Y64D | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
pncA pyrazinamidase | Y64S | - | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Candidate |
| Y95* | - | nonsense mutation | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| Y95D | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
| Y99* | - | nonsense mutation | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established |
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