Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB β subunit of RNA polymerase	D473N	-	-	Listeria monocytogenes	rifampicin	Reslit	Candidate
rpoB DNA-directed RNA polymerase beta chain	D477Y	-	-	Flavobacterium psychrophilum	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	D479E	-	-	Helicobacter pylori	rifabutin	Reslit	Candidate
rpoB RNA polymerase beta subunit	D483G	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB β subunit of RNA polymerase	D489V	-	-	Streptococcus pneumoniae	rifampicin	Reslit	Candidate
rpoB	D492N	-	single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Clostridium ljungdahlii, Clostridioides difficile	rifampicinrifaximin	Card DatabaseReference Gene Catalog	Confirmed
rpoB DNA-directed RNA polymerase beta subunit	D492V	-	single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Clostridium difficile, Clostridium ljungdahlii, Clostridioides difficile	rifampicinrifaximin	Card DatabaseReference Gene CatalogReslit	Confirmed
rpoB	D492Y	-	DNA-directed RNA polymerase subunit beta RpoB	Clostridioides difficile	rifaximin	Reference Gene Catalog	Established
rpoB RNA polymerase beta subunit	D516A	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Supported
rpoB RNA polymerase beta subunit	D516E	-	-	Mycobacterium tuberculosis, Mycobacterium smegmatis	rifampicinrifabutin	Reslit	Supported