Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	D516del	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	D516F	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Supported
rpoB RNA polymerase beta subunit	D516G	A1548G G1547A	DNA-directed RNA polymerase subunit beta RpoB	Mycobacterium tuberculosis, Escherichia coli, E. coli, Pseudomonas aeruginosa, Pseudomonas fluorescens, Mycobacterium smegmatis, Salmonella enterica, Shigella sonnei	rifampicinrifabutin	Reference Gene CatalogReslit	Confirmed
rpoB β subunit of RNA polymerase	D516H	-	-	Mycobacterium smegmatis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	D516L	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	D516N	-	-	Escherichia coli, Mycobacterium smegmatis, Mycobacterium tuberculosis	rifampicinrifabutinrifapentine	Reslit	Supported
rpoB DNA-directed RNA polymerase subunit beta	D516T	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	D516V	A1549T GAC-GTC A1548T GAT->GTT	-	Mycobacterium tuberculosis, Escherichia coli, Mycobacterium smegmatis, Rhodococcus equi, Mycobacterium gastri	rifampicinrifabutinethambutol	Reslit	Supported
rpoB RNA polymerase beta subunit	D516Y	GAC-TAC GAT->TAT	-	Mycobacterium tuberculosis, Escherichia coli	rifampicinrifabutin	Reslit	Supported
rpoB β-subunit of RNA polymerase	D521A	-	-	Pseudomonas fluorescens	rifampicin	Reslit	Candidate