Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
bla CMY-16 beta-lactamase | Y150S | - | reduced inhibition efficacy of avibactam | Klebsiella pneumoniae | aztreonamavibactam | Reslit | Candidate |
bla KPC Beta-lactamase | D179Y | - | - | Klebsiella pneumoniae | carbapenems | Reslit | Candidate |
bla OXY beta-lactamase | - | - | - | ceftriaxone | Reslit | Candidate | |
bla OXY beta-lactamase | - | - | - | ceftriaxone | Reslit | Candidate | |
bla TEM-1 beta-lactamase | - | increases expression | Escherichia coli | amoxicillin clavulanic acid | Reslit | Candidate | |
bla TEM-1 beta-lactamase | - | increases expression | Escherichia coli | amoxicillin clavulanic acid | Reslit | Candidate | |
bla TEM-30 beta-lactamase | R244S | - | - | Escherichia coli | amoxicillinticarcillin | Reslit | Candidate |
bla(KLUC) β-lactamase | D240G | - | - | Klebsiella pneumoniae, Escherichia coli | cefotaximeceftazidimeceftriaxone | Reslit | Candidate |
bla(KLUC) β-lactamase | S18G | - | - | Klebsiella pneumoniae, Escherichia coli | cefotaximeceftriaxone | Reslit | Candidate |
bla(KPC-2) beta-lactamase | D179Y | - | confers resistance to ceftazidime/avibactam without loss of carbapenem resistance | Pseudomonas aeruginosa | ceftazidime avibactam | Reslit | Candidate |
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