Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| L443W | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card DatabaseResFinder Database | Confirmed | |
rpoB RNA polymerase beta subunit | L449M | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card DatabaseReslit | Confirmed |
rpoB DNA-directed RNA polymerase subunit beta | L449P | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
| L449Var | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card Database | Established | |
rpoB RNA polymerase beta subunit | L450P | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
| L452M | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card Database | Established | |
rpoB RNA-polymerase beta-subunit | L452P | single resistance variant | Mycobacterium tuberculosis, Mycobacterium smegmatis, Mycobacterium bovis | rifampicinrifabutin | Card DatabaseResFinder DatabaseReslit | Confirmed | |
rpoB RNA polymerase beta subunit | L452Q | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
| L452R | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card Database | Established | |
| L452V | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card Database | Established |
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