Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB	L452Var	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB RNA polymerase beta subunit	L455P	-	-	Mycobacterium leprae	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L456I	-	-	-	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L457P	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card DatabaseResFinder DatabaseReslit	Confirmed
rpoB	L457R	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB RNA polymerase beta subunit	L461V	-	-	Chlamydia trachomatis	rifampicin	Reslit	Candidate
rpoB beta subunit of RNA polymerase	L463I	-	-	Streptomyces lydicus, Streptomyces spectabilis	streptovaricinrifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L464M	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card DatabaseResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	L466S	CTG->TCA	Target modification, single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus, Staphylococcus epidermidis	rifampicinvancomycinteicoplanin+1 more	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB beta subunit of RNA polymerase	L478S	-	-	Chlamydia pneumoniae	rifampicinrifalazil	Reslit	Candidate