Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	T593A	-	-	Helicobacter pylori	rifabutin	Reslit	Candidate
rpoB RNA polymerase beta subunit	T593K	-	-	Helicobacter pylori	rifabutin	Reslit	Candidate
rpoB RNA polymerase beta subunit	T622I	-	-	Staphylococcus aureus	oxacillin	Reslit	Candidate
rpoB RNA polymerase beta subunit	T634K	-	upregulation of a previously uncharacterized operon (prdRAB) that leads to cell membrane remodelling and cross-resistance to daptomycin through reduced binding of the antibiotic	Enterococcus faecium	daptomycin	Reslit	Candidate
rpoB beta subunit of RNA polymerase	T638K	-	-	Streptomyces lydicus, Streptomyces spectabilis	rifampicin	Reslit	Candidate
rpoB	T676P	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB DNA/RNA polymerase subunit	V1016E	-	-	Staphylococcus aureus	oxacillin	Reslit	Candidate
rpoB RNA polymerase beta subunit	V1032I	-	-	Staphylococcus pseudintermedius	vancomycin	Reslit	Candidate
rpoB	V1143D	-	DNA-directed RNA polymerase subunit beta RpoB	Clostridioides difficile	fidaxomicin	Reference Gene Catalog	Established
rpoB	V1143F	-	DNA-directed RNA polymerase subunit beta RpoB	Clostridioides difficile	fidaxomicin	Reference Gene Catalog	Established