Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB	V1143G	-	DNA-directed RNA polymerase subunit beta RpoB	Clostridioides difficile	fidaxomicin	Reference Gene Catalog	Established
rpoB	V1143L	-	DNA-directed RNA polymerase subunit beta RpoB	Clostridioides difficile	fidaxomicin	Reference Gene Catalog	Established
rpoB RNA polymerase beta subunit	V136F	-	-	Chlamydia trachomatis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	V144M	-	-	Mycobacterium tuberculosis	rifabutin	Reslit	Candidate
rpoB RNA polymerase beta subunit	V146F	GTT->TTC	Target modification, single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Mycobacterium tuberculosis, Escherichia coli, Shigella sonnei	rifampicinrifabutinrifamycins	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB	V148I	-	multiple resistance variants	Helicobacter pylori	rifampicin	Card Database	Established
rpoB	V149D	-	single resistance variant	Helicobacter pylori	rifampicin	Card Database	Established
rpoB	V149E	-	single resistance variant	Helicobacter pylori	rifampicin	Card Database	Established
rpoB Beta-subunit of RNA polymerase	V149F	-	single resistance variant, multiple resistance variants	Helicobacter pylori	rifampicinrifabutin	Card DatabaseReslit	Confirmed
rpoB	V149K	-	single resistance variant	Helicobacter pylori	rifampicin	Card Database	Established