Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
rpoC RNA polymerase gamma subunit | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate | |
rpoC RNA polymerase gamma subunit | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate | |
rpoC RNA polymerase gamma subunit | A172V | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
rpoC RNA polymerase beta' subunit | A521D | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
rpoC RNA polymerase (α subunit) | A734V | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card DatabaseReslit | Confirmed |
| A738T | - | DNA-directed RNA polymerase subunit beta RpoC | Staphylococcus aureus | beta lactams | Reference Gene Catalog | Established | |
rpoC alpha subunit of RNA polymerase | A787V | - | - | Escherichia coli | rifampicin | Reslit | Candidate |
| D1127E | - | DNA-directed RNA polymerase subunit beta RpoC | Clostridioides difficile | fidaxomicin | Reference Gene Catalog | Established | |
| D237Y | - | DNA-directed RNA polymerase subunit beta RpoC | Clostridioides difficile | fidaxomicin | Reference Gene Catalog | Established | |
| D244Y | - | single resistance variant | Clostridioides difficile | vancomycin | Card Database | Established |
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