Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Reslit |
| Candidate |
| S531K | - | - | - | Rifampicin | Reslit | Candidate |
| S531L | disrupted the intermolecular hydrogen bond between wild-type Ser531 and the RIF molecule, reduces susceptibility, disorders the RIF-binding pocket upon RMP binding and therefore reduces the binding affinity for RMP | Mycobacterium tuberculosis, Mycobacterium simiae, Mycobacterium smegmatis, Rhodococcus equi, Escherichia coli, Mycobacterium avium, Salmonella enterica, Mycobacterium bovis | RifampinRifampicin|RifabutinRifampicin+3 more | Reslit | Supported |
| S531P | - | - | Mycobacterium tuberculosis | Rifampicin | Reslit | Candidate |
| S531Q | - | Mycobacterium tuberculosis | Rifampin | Reslit | Candidate |
| S531R | - | - | - | Rifampicin | Reslit | Candidate |
| S531T | - | - | Mycobacterium tuberculosis | Rifampin | Reslit | Candidate |
| S531W | - | Mycobacterium tuberculosis, Mycobacterium smegmatis, Rhodococcus equi, Mycobacterium avium | RifampinRifampin|RifabutinRifampicin | Reslit | Supported |
| S531Y | - | - | Mycobacterium tuberculosis, Mycobacterium avium, Mycobacterium bovis | RifampinRifampicin | Reslit | Supported |
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