Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
rpoC RNA polymerase gamma subunit | E1140D | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
rpoC RNA polymerase subunit beta' | E368K | - | - | Escherichia coli | ampicillinrifampicin | Reslit | Candidate |
rpoC RNA polymerase gamma subunit | E750D | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
| E750Q | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card Database | Established | |
rpoC β'-subunit of RNA polymerase | E854K | - | - | Staphylococcus aureus | daptomycin | Reslit | Candidate |
| E933Q | - | DNA-directed RNA polymerase subunit beta RpoC | Staphylococcus aureus | beta lactams | Reference Gene Catalog | Established | |
rpoC RNA polymerase beta' subunit | F452L | - | Mycobacterium smegmatis, Mycobacterium tuberculosis | rifampicin | Reslit | Supported | |
| F452S | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card DatabaseResFinder Database | Confirmed | |
rpoC RNA polymerase omega subunit | F632S | - | single resistance variant, DNA-directed RNA polymerase subunit beta RpoC | Staphylococcus aureus | vancomycindaptomycin | Card DatabaseReference Gene CatalogReslit | Confirmed |
rpoC RNA polymerase, beta prime subunit | F86C | - | - | fluoroquinolones | Reslit | Candidate |
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