Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
blaNDM metallobeta-lactamase	M154L	-	enhances Zn(II) binding affinity	Escherichia coli	carbapenemspenicillincephalosporins	Reslit	Candidate
blaNDM metallobeta-lactamase	M154V	-	enhances Zn(II) binding affinity	Escherichia coli	carbapenemspenicillincephalosporins	Reslit	Candidate
blaOXA-10 class D beta-lactamase	V117L	-	enhances carbapenemase activity	Escherichia coli, Enterobacter cloacae	meropenemertapenemdoripenem+1 more	Reslit	Candidate
blaOXA-193 oxacillinase	-	G-57T	up-regulation of bla OXA and high-level ß-lactam resistance	Campylobacter coli, Campylobacter jejuni	ampicillin	Reslit	Candidate
blaOXA-23 OXA carbapenemase	H121R	-	-	-	carbapenems	Reslit	Candidate
blaOXA-23 class D serine beta-lactamase	V128L	GTT -> TTG	-	-	carbapenems	Reslit	Candidate
blaOXA-24 β-lactamase	M223A	-	-	Acinetobacter baumannii	carbapenems	Reslit	Candidate
blaOXA-24 class D beta-lactamase	Y112A	-	reduces resistance	Acinetobacter baumannii	imipenemmeropenemcarbapenems	Reslit	Candidate
blaOXA-423 carbapenemase	V128A	-	weaker hydrolytic capacity	Acinetobacter baumannii, E. coli	penicillincarbapenems	Reslit	Candidate
blaOXA-48-like carbapenemase	E168Q	-	-	Klebsiella pneumoniae, Escherichia coli, Enterobacter aerogenes, Enterobacter cloacae	carbapenems	Reslit	Candidate