Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpsL ribosomal protein S12	K121K	-	-	Mycobacterium tuberculosis	streptomycin	Reslit	Supported
rpsL ribosomal protein S12	K15N	-	-	Mycobacterium tuberculosis	streptomycin	Reslit	Candidate
rpsL ribosomal protein S12	K172T	A514C	-	-	streptomycin	Reslit	Candidate
rpsL ribosomal protein S12	K247N	-	-	Mycobacterium tuberculosis	ofloxacin	Reslit	Candidate
rpsL 30S ribosomal protein S12	K338R	-	-	Mycoplasma mycoides	streptomycin	Reslit	Candidate
rpsL ribosomal protein S12	K42A	-	-	Escherichia coli	streptomycin	Reslit	Candidate
rpsL ribosomal protein S12	K42N	-	impairs ribosome performance, reduces susceptibility	Salmonella enterica, Escherichia coli, Mycobacterium tuberculosis	streptomycin	Reslit	Supported
rpsL ribosomal protein S12	K42R	-	retains wild-type translation rate	Escherichia coli, Salmonella enterica, Mycobacterium tuberculosis, Mycobacterium smegmatis	streptomycin	Reslit	Supported
rpsL ribosomal protein S12	K43M	-	-	Mycobacterium smegmatis, Mycobacterium tuberculosis	streptomycin	Reslit	Candidate
rpsL ribosomal protein S12	K43N	A128T A131C	-	Escherichia coli, Mycobacterium smegmatis, Mycobacterium tuberculosis	streptomycinamikacingentamicin+2 more	Reslit	Supported