Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
carD protein | R25E | - | weakens interaction with RNAP | Mycobacterium smegmatis, Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
carD protein | R47E | - | weakens interaction with RNAP | Mycobacterium smegmatis, Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
carO porin | D389V | - | - | - | tetracycline | Reslit | Candidate |
carO porin | I65V | - | - | - | tetracycline | Reslit | Candidate |
carO porin | R170G | - | - | - | tetracycline | Reslit | Candidate |
carO porin | T438P | - | - | - | tetracycline | Reslit | Candidate |
cat chloramphenicol acetyltransferase | A138T | - | enhanced thermostability | Geobacillus kaustophilus, Staphylococcus aureus | phenicols | Reslit | Candidate |
cat chloramphenicol acetyltransferase | H193A | - | - | E. coli | phenicols | Reslit | Candidate |
cat chloramphenicol acetyltransferase | H79A | significantly reduces CAT activity and chloramphenicol resistance | Riemerella anatipestifer, Escherichia coli | phenicols | Reslit | Candidate | |
cat chloramphenicol acetyltransferase | T172A | - | E. coli, Escherichia coli | phenicols | Reslit | Candidate |
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